Accelerated prompt gamma estimation for clinical proton therapy simulations

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Prompt High-Energy Emission from Proton-Dominated Gamma-Ray Bursts

The prompt emission of gamma-ray bursts (GRBs) is widely thought to be radiation from accelerated electrons, but an appreciably larger amount of energy could be carried by accelerated protons, particularly if GRBs are the sources of ultra-high-energy cosmic rays (UHECRs). We model the expected photon spectra for such “proton-dominated” GRBs in the internal shock scenario through Monte Carlo sim...

متن کامل

Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring

Monte Carlo tools have been long used to assist the research and development of solutions for proton therapy monitoring. The present work focuses on the prompt-gamma emission yields by comparing experimental data with the outcomes of the current version of Geant4 using all applicable proton inelastic models. For the case in study and using the binary cascade model, it was found that Geant4 over...

متن کامل

Quantitative analysis of prompt gamma ray imaging during proton boron fusion therapy according to boron concentration

The purpose of this study is to evaluate the prompt gamma ray imaging technique according to the clinical boron concentration range during proton boron fusion therapy (PBFT). To acquire a prompt gamma ray image from 32 projections, we simulated four head single photon emission computed tomography and a proton beam nozzle using a Monte Carlo simulation. We used modified ordered subset expectatio...

متن کامل

Machine learning-based patient specific prompt-gamma dose monitoring in proton therapy.

Online dose monitoring in proton therapy is currently being investigated with prompt-gamma (PG) devices. PG emission was shown to be correlated with dose deposition. This relationship is mostly unknown under real conditions. We propose a machine learning approach based on simulations to create optimized treatment-specific classifiers that detect discrepancies between planned and delivered dose....

متن کامل

Compton Camera and Prompt Gamma Ray Timing: Two Methods for In Vivo Range Assessment in Proton Therapy

Proton beams are promising means for treating tumors. Such charged particles stop at a defined depth, where the ionization density is maximum. As the dose deposit beyond this distal edge is very low, proton therapy minimizes the damage to normal tissue compared to photon therapy. Nevertheless, inherent range uncertainties cast doubts on the irradiation of tumors close to organs at risk and lead...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Physics in Medicine and Biology

سال: 2016

ISSN: 0031-9155,1361-6560

DOI: 10.1088/0031-9155/61/21/7725